For decades AI research was a relatively fringe domain of computer science. Its proponents often trafficked in prophetic predictions that AI would eventually bring about the dawn of superhuman intelligence. Suddenly, in the past few years, those visions have become vivid. The advent of large language models with powerful generative capabilities has led to speculation about encroachment on all branches of human achievement. AIs can receive a prompt and spit out illustrations, essays, solutions to complex math problems—and, now, Nobel-winning discoveries. Have AIs taken over the science Nobels and possibly science itself?